Selection Of The Amount Of Adhesive

According to the minimum required for the tablet to reach a certain hardness, friability or dissolution rate, determine the amount of binder. Generally, increasing the viscosity will increase the hardness of the tablet and reduce the friability and dissolution rate. There are two ways to increase the amount of adhesive: increasing the amount of adhesive solution and increasing the concentration of the adhesive solution. Under the same granulation effect, increasing the amount of binder solution uses less binder than increasing the concentration of the binder solution. However, increasing the amount of binder solution may cause the soft material to overwet.